Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression A mutation in this gene

A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia

Rac interactive binding) domain

tissue specificity:Ubiquitously expressed with higher expression found in heart and placenta

which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration

Rat E3 Ubiquitin-protein Ligase Trim63, TRIM63 ELISA Kit, 96T Mammalian Expression A mutation in this geneE3 ubiquitin ligase. Mediates the ubiquitination and subsequent proteasomal degradation of CKM, GMEB1 and HIBADH. Regulates the proteasomal degradation of muscle proteins under amino acid starvation, where muscle protein is catabolized to provide other organs with amino acids. Inhibits de novo skeletal muscle protein synthesis under amino acid starvation. Regulates proteasomal degradation of cardiac troponin I TNNI3 and probably of other sarcomeric