Cathepsin E Polyclonal Antibody, 20ul Cell Biology Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different proteins have been identified

specifically through a caspase-dependent pathway

The protein encoded by MYBL2

and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium

Cathepsin E Polyclonal Antibody, 20ul Cell Biology Alternatively spliced transcript variants encodingCTSE encodes a member of the A1 family of peptidases. Alternative splicing of CTSE results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme (cathepsin E), an aspartic endopeptidase, may be involved in antigen processing and the maturation of secretory proteins. Elevated expression of CTSE has been observed in neurodegeneration.