PDE2A Polyclonal Antibody, 20ul Liquid Handling ＆Storage The encoded protein interacts with

The encoded protein interacts with IRS1 protein| suggesting a role in regulating insulin sensitivity

The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth

This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair

May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly

PDE2A Polyclonal Antibody, 20ul Liquid Handling ＆Storage The encoded protein interacts withalternative products: Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,Catalytic activity: Nucleoside 3',5' cyclic phosphate + H(2)O = nucleoside 5' phosphate.,Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,Belongs to the cyclic nucleotide phosphodiesterase family.,Contains 2 GAF domains.,subunit: Homodimer.,tissue specificity: Expressed in brain and to a lesser extent in heart, placenta, lung,