Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment Many alternatively spliced transcript variants

Many alternatively spliced transcript variants exist for this gene

GPR35 (G protein-coupled receptor 35) is a 309 amino acid multi-pass membrane protein that belongs to the G-protein coupled receptor 1 family

this receptor mediates calcium release from the endoplasmic reticulum

GO annotations related to this gene include poly(A) RNA binding and methylated histone binding

Dkk-1 Monoclonal Antibody, 50ul In vitro Assessment Many alternatively spliced transcript variantsThis gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.