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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification This gene contains sequences homologous

SKU: 22639030587

4.7
SEK97.20 SEK133.20

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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification This gene contains sequences homologousCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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Description

This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis

The cytogenetic location of this locus has been reported as both 8p11 and 8q11

and to a lesser degree

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PDK1(Phospho Ser241) Polyclonal Antibody, 20ul Protein Post-translational Modification This gene contains sequences homologousCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,

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