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OPA1 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Phosphorylation by protein kinase C

SKU: 21915416198

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OPA1 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Phosphorylation by protein kinase CThis gene product is a nuclear encoded mitochondrial protein with similarity to dynamin related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane

Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion

it is required to recruit USP22 and ENY2 into the SAGA complex

Recent reports show that this protein is found both in the cytosol and the mitochondria

OPA1 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos Phosphorylation by protein kinase CThis gene product is a nuclear encoded mitochondrial protein with similarity to dynamin related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

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