Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter targeting the integrin for internalization

targeting the integrin for internalization and degradation

The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E

The upstream stimulatory factor 2 can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs and is involved in regulating multiple cellular processes

This gene forms the basis for the Kidd blood group system

Nibrin Polyclonal Antibody, 100ul[BT-AP06022] Syringe Filter targeting the integrin for internalizationMutations in NBN are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. Nibrin is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. NBN product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint activation.