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FAM111B Polyclonal Antibody, 20ul Cell Dissociation Equipped with an upper cover

SKU: 2140320590

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FAM111B Polyclonal Antibody, 20ul Cell Dissociation Equipped with an upper coverFAM111B encodes a protein with a trypsin like cysteine serine peptidase domain in the C terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog

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Description

Equipped with an upper cover

and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway

This protein was shown to interact with mitotic checkpoint proteins including Mad2

G-protein-coupled (EDG) receptor gene family

FAM111B Polyclonal Antibody, 20ul Cell Dissociation Equipped with an upper coverFAM111B encodes a protein with a trypsin like cysteine serine peptidase domain in the C terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog

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