Phospho-20S Proteasome Alpha3 (S250) Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The origin recognition complex (ORC)

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells

and tumor growth and metastasis

This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III

Two alternatively spliced transcript variants

Phospho-20S Proteasome Alpha3 (S250) Polyclonal Antibody, 50ul Nucleic Acid Isolation & Purification The origin recognition complex (ORC)The proteasome is a multicatalytic proteinase complex with a highly ordered ring shaped 20S core structure. The core structure is composed of 4 rings of 28 non identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP ubiquitin dependent process in a non lysosomal pathway. An essential function