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CDT1 Polyclonal Antibody, 100ul Bottles Mutations in this gene have

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CDT1 Polyclonal Antibody, 100ul Bottles Mutations in this gene haveThe protein encoded by this gene is involved in the formation of the pre replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A dependent kinases results in degradation of the protein.

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Description

Mutations in this gene have been associated with gnathodiaphyseal dysplasia

EPS8L2 encodes a member of the EPS8 gene family

It dissociates in S phase when LIN9| LIN37| LIN52 and LIN54 form a subcomplex that binds to MYBL2

It was reported to have phosphorylation-dependent DNA-primase activity

CDT1 Polyclonal Antibody, 100ul Bottles Mutations in this gene haveThe protein encoded by this gene is involved in the formation of the pre replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A dependent kinases results in degradation of the protein.

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