Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos the encoded protein may contribute

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

It is highly expressed in many cancers

and murine studies suggest a role in tumor-associated tissue remodeling

GPR135 (G Protein-Coupled Receptor 135) is a Protein Coding gene

Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos the encoded protein may contributeThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.