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RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression PC encodes pyruvate carboxylase

SKU: 20090423847

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RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression PC encodes pyruvate carboxylaseThis gene encodes a male meiotic metaphase chromosome associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia 24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Description

PC encodes pyruvate carboxylase

This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2

The phosphorylated form of this protein forms a complex with SMAD4| which is important for its function in the transcription regulation

Two related pseudogenes have been identified on chromosome 14

RSPH1 Polyclonal Antibody, 20ul Recombinant Protein Expression PC encodes pyruvate carboxylaseThis gene encodes a male meiotic metaphase chromosome associated acidic protein. This gene is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in this gene result in primary ciliary dyskinesia 24. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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