ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation Alternatively spliced transcript variants have

Alternatively spliced transcript variants have also been noted for this gene

Mutations in this gene have been associated with familial dysautonomia

dystrophin RNA is differentially spliced

The encoded protein is homologous with two proteins that bind to the retinoblastoma gene product

ATG10 Polyclonal Antibody, 100ul Immune Cell Preparation Alternatively spliced transcript variants haveAutophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2 like enzyme involved in 2 ubiquitin like modifications essential for autophagosome formation: ATG12 (MIM 609608) ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane bound form (Nemoto et al., 2003