RUNX1 Polyclonal Antibody, 50ul[BT-AP08058] Gene Synthesis Mutations in TBX3 cause ulnar-mammary

Mutations in TBX3 cause ulnar-mammary syndrome

This intronless gene TSSK6 (testis specific serine kinase 6) encodes a member of the CAMK (calcium/calmodulin-dependent) serine/threonine protein kinase family

and for interactions with other proteins

A polymorphism in the promoter of this gene may be linked to an increased risk of X-linked mental retardation

RUNX1 Polyclonal Antibody, 50ul[BT-AP08058] Gene Synthesis Mutations in TBX3 cause ulnar-mammaryCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three