EDG-3 Polyclonal Antibody, 50ul[BT-AP02828] Molecular Weight Markers This single chain zymogen is

This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain

It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases

Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids

Also it may be involved in signal transduction

EDG-3 Polyclonal Antibody, 50ul[BT-AP02828] Molecular Weight Markers This single chain zymogen isS1PR3 encodes a member of the EDG family of receptors, which are G protein coupled receptors. This protein has been identified as a functional receptor for sphingosine 1 phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.