Phospho-Abl1 (T735) Polyclonal Antibody, 50ul Drying & Desiccation Variation in this gene has

Variation in this gene has been associated with cerebellar ataxia

The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family

This gene is mapped to a candidate region of chromosome 4 which may be associated with bipolar disorder and schizophrenia

Polymorphisms in this gene have been linked to breast and prostate cancer

Phospho-Abl1 (T735) Polyclonal Antibody, 50ul Drying & Desiccation Variation in this gene hasABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is regulated by CDC2 mediated phosphorylation, suggesting a