GMIP Rabbit Polyclonal Antibody, 20ul Protein Modification ARHGAP22 (Rho GTPase activating protein

ARHGAP22 (Rho GTPase activating protein 22) encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins

The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia

Signal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal-regulatory-protein (SIRP) family

Cleavage stimulation factor subunit 2 is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs

GMIP Rabbit Polyclonal Antibody, 20ul Protein Modification ARHGAP22 (Rho GTPase activating proteinThis gene encodes a member of the ARHGAP family of Rho Rac Cdc42 like GTPase activating proteins. The encoded protein interacts with the Ras related protein Gem through its N terminal domain. Separately it interacts with RhoA through a RhoGAP domain and stimulates RhoA dependent GTPase activity. Alternative splicing results in multiple transcript variants.