EP-CAM Polyclonal Antibody, 100ul[BT-AP02986] Cryopreservation promotes p53/TP53 phosphorylation on ‘Ser-46'
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EP-CAM Polyclonal Antibody, 100ul[BT-AP02986] Cryopreservation promotes p53/TP53 phosphorylation on ‘Ser-46'EPCAM encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in EPCAM result in congenital tufting enteropathy.
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