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HES5 Polyclonal Antibody, 100ul sgRNA customized design Josephin domain-containing proteins are deubiquitinating

SKU: 18957649219

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HES5 Polyclonal Antibody, 100ul sgRNA customized design Josephin domain-containing proteins are deubiquitinatingThis gene encodes a member of a family of basic helix loop helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.

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Description

Josephin domain-containing proteins are deubiquitinating enzymes which catalyze the hydrolysis of the bond between the C-terminal glycine of the ubiquitin peptide and protein substrates

but not to the corresponding alcohols

RPL14 (ribosomal protein L14) encodes a ribosomal protein that is a component of the 60S subunit

It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells

HES5 Polyclonal Antibody, 100ul sgRNA customized design Josephin domain-containing proteins are deubiquitinatingThis gene encodes a member of a family of basic helix loop helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.

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