Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for this gene

This is the rate-limiting step in the de novo synthesis of guanine nucleotides

The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux

often at the N- or C-terminus of the protein

Mcl-1(Phospho-Ser159/Thr163) Rabbit Polyclonal Antibody, 50ul Immune Cell Preparation Alternatively spliced transcript variants encodingThis gene encodes an anti apoptotic protein which is a member of the Bcl 2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death inducing.