PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies The BRCA1-A complex possesses ubiquitinase

The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks

Alternate splicing of this gene generates several transcript variants encoding different isoforms

is required for the apoptosis mediated by this protein

The receptor is primarily located in the anterior pituitary

PO2F3 Rabbit Polyclonal Antibody, 100ul Organelle Studies The BRCA1-A complex possesses ubiquitinaseThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene