RANKL Polyclonal Antibody, 50ul[BT-AP07786] Molecular Sciences Cytoplasmic dynein 1 acts as
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RANKL Polyclonal Antibody, 50ul[BT-AP07786] Molecular Sciences Cytoplasmic dynein 1 acts asThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.
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