Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation DDX52 is phosphorylated by ATM

DDX52 is phosphorylated by ATM or ATR upon DNA damage

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi

This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation

The encoded protein is secreted through the plasma membrane but remains membrane-bound

Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody, 100ul Drying & Desiccation DDX52 is phosphorylated by ATMThis gene encodes a protein that regulates autophagy a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol 3 kinase (PI3K) complex which mediates vesicle trafficking processes. This protein is thought to play a role in multiple cellular processes including tumorigenesis neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.