Arkadia Polyclonal Antibody, 100ul Hepatocytes The transcribed messenger RNA contains

The transcribed messenger RNA contains two upstream open reading frames (ORFs) that repress translation of the main protein coding ORF under normal conditions

Additional isoforms have been described for this gene but they have not yet been experimentally verified

cell cycle regulation and chromatin remodeling [PMID: 17486619]

is essential for development and survival of mast cells in vivo

Arkadia Polyclonal Antibody, 100ul Hepatocytes The transcribed messenger RNA containsThe protein encoded by RNF111 (ring finger protein 111) is a nuclear RING domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) beta NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF beta target gene transcription. As a modulator of the nodal signaling cascade, RNF111 plays a critical role in the