ENA-78 Polyclonal Antibody, 50ul Culture Media The VAV proteins are guanine

The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations

Polymorphisms in this gene have been associated with Alzheimer's disease

and may have an important role as a potential gene therapy target

A pseudogene of this gene has been defined on chromosome 4

ENA-78 Polyclonal Antibody, 50ul Culture Media The VAV proteins are guanineThis gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G protein coupled receptor chemokine (C X C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell