Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation is retained in cytoplasm by

is retained in cytoplasm by YWHAZ

contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

a triple coiled-coil repeat central region

Nibrin(Phospho Ser278) Polyclonal Antibody, 100ul Plasmid Preparation is retained in cytoplasm byMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint