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Rpb1 CTD(Phospho-Ser7) Rabbit Polyclonal Antibody, 100ul Pipette Controller Knockout mice lacking this gene

SKU: 16391325843

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Rpb1 CTD(Phospho-Ser7) Rabbit Polyclonal Antibody, 100ul Pipette Controller Knockout mice lacking this geneThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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Description

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

This protein plays a role in diverse cellular functions

Each pouch contains 1L of concentrated solution

3 and are known to be highly polymorphic

Rpb1 CTD(Phospho-Ser7) Rabbit Polyclonal Antibody, 100ul Pipette Controller Knockout mice lacking this geneThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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