Human E3 Ubiquitin-protein Ligase Mylip, MYLIP ELISA Kit, 96T Biomatrix Individuals homozygous for a mutation

Individuals homozygous for a mutation in this gene are at higher risk for type 2 diabetes and have higher levels of circulating glucose and insulin levels after glucose ingestion

Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells (Probable) (PubMed: 10653850)

promotes p53/TP53 phosphorylation on ‘Ser-46' and subsequent apoptosis

plays a key role in telomeric loop (T loop) formation by generating 3' single-stranded overhang at the leading end telomeres: T loops have been proposed to protect chromosome ends from degradation and repair

Human E3 Ubiquitin-protein Ligase Mylip, MYLIP ELISA Kit, 96T Biomatrix Individuals homozygous for a mutation