EphB6 Polyclonal Antibody, 20ul Serum FERM RhoGEF and pleckstrin domain-containing

FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1

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An important paralog of this gene is SCNN1G

EphB6 Polyclonal Antibody, 20ul Serum FERM RhoGEF and pleckstrin domain-containingEPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin B family proteins. Unlike other members of this family, the encoded protein (EPH receptor B6) does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis.