TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Activation of HIV-1 gene expression

Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site

One of these

Variable expression of RPS5 in colorectal cancers compared to adjacent normal tissues has been observed

but lacks the active site lysine and probably lacks a catalytic function

TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul Adeno-associated Virus Packaging Activation of HIV-1 gene expressionCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only