p16 Polyclonal Antibody, 100ul[BT-AP06744] Endonucleases & Exonucleases Alternative promoter usage and splicing

Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2

The soluble isoforms are associated with the onset of pre-eclampsia

Alternatively spliced transcript variants encoding different isoforms have been found for GYS1

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication

p16 Polyclonal Antibody, 100ul[BT-AP06744] Endonucleases & Exonucleases Alternative promoter usage and splicingCDKN2A (cyclin dependent kinase inhibitor 2A) generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an