S10AE Polyclonal Antibody, 20ul Biochemical Reagents NEIL2 belongs to a class

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family

This gene is a MAGE-B subfamily member of the MAGE gene family

Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5)

This gene is a candidate for the ovarian tumor suppressor gene

S10AE Polyclonal Antibody, 20ul Biochemical Reagents NEIL2 belongs to a classThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).