PLC gamma2(Phospho Tyr1217) Polyclonal Antibody, 20ul Funnels and pertussis toxin-sensitive manner

and pertussis toxin-sensitive manner

Two transcript variants encoding the same protein but differing in the 5' UTR| have been found for this gene

Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease

Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease

PLC gamma2(Phospho Tyr1217) Polyclonal Antibody, 20ul Funnels and pertussis toxin-sensitive mannerThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in