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Integrin AlphaL Polyclonal Antibody, 20ul Transporters Evidence indicates that mutations in

SKU: 15050067624

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Integrin AlphaL Polyclonal Antibody, 20ul Transporters Evidence indicates that mutations inITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3

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Description

Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1)

angiogenesis

This protein causes differentiation of brain cells

The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury

Integrin AlphaL Polyclonal Antibody, 20ul Transporters Evidence indicates that mutations inITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function associated antigen 1 (LFA 1), which is expressed on all leukocytes. LFA 1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1 3

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