CD1e Polyclonal Antibody, 100ul[BT-AP01395] Diagnostic Probes & Oligos The encoded protein is localized

The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation

Several transcript variants encoding different isoforms have been found for this gene

Alternative splicing results in multiple transcripts variants

where it stimulates ACTH release

CD1e Polyclonal Antibody, 100ul[BT-AP01395] Diagnostic Probes & Oligos The encoded protein is localizedCD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta 2 microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought