PO2F3 Rabbit Polyclonal Antibody, 20ul Electrophoresis & Labeling CABLES1 encodes a protein (Cdk5

CABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

Many alternatively spliced transcript variants

or subcellular compartments such as lysosomes and endosomes

PO2F3 Rabbit Polyclonal Antibody, 20ul Electrophoresis & Labeling CABLES1 encodes a protein (Cdk5This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene