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API5 Polyclonal Antibody, 50ul Gene Synthesis The active site residues of

SKU: 14451815023

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API5 Polyclonal Antibody, 50ul Gene Synthesis The active site residues ofAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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Description

The active site residues of carboxypeptidases A and B are conserved in this protein

which is predicted to span the membrane four times

a type I keratin

it was discovered to be a human homolog of the E

API5 Polyclonal Antibody, 50ul Gene Synthesis The active site residues ofAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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