LDLR Polyclonal Antibody, 20ul Shaker&Mixing Mutations in this gene cause

Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2

Alternative splicing of KRT13 results in multiple transcript variants

muscle and other tissues is the hydrophilic species

Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors

LDLR Polyclonal Antibody, 20ul Shaker&Mixing Mutations in this gene causeThe low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3 hydroxy 3 methylglutaryl coenzyme A (HMG CoA) reductase, the rate limiting step