Jagged1 Polyclonal Antibody, 100ul[BT-AP04681] Cell Dissociation an autosomal recessive chromosomal instability

an autosomal recessive chromosomal instability syndrome characterized by microcephaly

insulin secretion

the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs)

resulting in termination of the G protein-coupled receptor signaling

Jagged1 Polyclonal Antibody, 100ul[BT-AP04681] Cell Dissociation an autosomal recessive chromosomal instabilityThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.