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SMCE1 Polyclonal Antibody, 50ul Culture Plate Inserts Found in liver

SKU: 13522322497

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SMCE1 Polyclonal Antibody, 50ul Culture Plate Inserts Found in liverThe protein encoded by this gene is part of the large ATP dependent chromatin remodeling complex SWI SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI SNF complex, can bind to 4 way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA binding HMG domain, but disruption of this domain

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Description

Found in liver

They bind to

This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein

Defects in this gene are the cause of LIG4 syndrome

SMCE1 Polyclonal Antibody, 50ul Culture Plate Inserts Found in liverThe protein encoded by this gene is part of the large ATP dependent chromatin remodeling complex SWI SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI SNF complex, can bind to 4 way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA binding HMG domain, but disruption of this domain

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