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PDK2 Polyclonal Antibody, 20ul Molecular Sciences pre- B-lymphocytes and bone marrow

SKU: 13434761587

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PDK2 Polyclonal Antibody, 20ul Molecular Sciences pre- B-lymphocytes and bone marrowPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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Description

pre- B-lymphocytes and bone marrow

but is not detected in normal kidney or most other normal tissues

childhood leukemia (t (19

This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria

PDK2 Polyclonal Antibody, 20ul Molecular Sciences pre- B-lymphocytes and bone marrowPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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