NISCH Rabbit Polyclonal Antibody, 20ul Sampling Tubes Another variant encoding an N-terminally

Another variant encoding an N-terminally truncated isoform has been reported

The protein encoded by this gene contains two doublecortin domains| which bind microtubules and regulate microtubule polymerization

In this form| it circulates in the plasma| prolonging the half-life of IGFs and altering their interaction with cell surface receptors

The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation

NISCH Rabbit Polyclonal Antibody, 20ul Sampling Tubes Another variant encoding an N-terminallyThis gene encodes a nonadrenergic imidazoline 1 receptor protein that localizes to the cytosol and anchors to the inner layer of the plasma membrane. The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha 5 beta 1 integrin. In humans this protein has been shown to bind to the adapter insulin receptor substrate 4 (IRS4) to mediate translocation of alpha 5 integrin from the cell