UCH-L1 Polyclonal Antibody, 50ul[BT-AP15341] Vortex Mixer Defects in this gene are

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

The gene has been associated with lung cancer risk

cerebellum and amygdala

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)

UCH-L1 Polyclonal Antibody, 50ul[BT-AP15341] Vortex Mixer Defects in this gene areThe protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.