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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges ABL1 has been found fused

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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges ABL1 has been found fusedATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

ABL1 has been found fused to a variety of translocation partner genes in various leukemias

or alternatively

hepatitis C virus (HCV)

May be involved in fusion of ER-derived transport vesicles with the Golgi complex

Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 20ul Palm Micro Centrifuges ABL1 has been found fusedATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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