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IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 100ul[BT-AP08801] Cell Senescence induction:Up-regulated upon retinoic acid

SKU: 13003199793

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IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 100ul[BT-AP08801] Cell Senescence induction:Up-regulated upon retinoic acidThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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Description

induction:Up-regulated upon retinoic acid

which results in the inhibition of the mammalian target of rapamycin protein

It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide

Involved in the renal elimination of endogenous and exogenous organic anions

IGF-IR(Phospho Tyr1161) Polyclonal Antibody, 100ul[BT-AP08801] Cell Senescence induction:Up-regulated upon retinoic acidThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have

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