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CD59 Polyclonal Antibody, 100ul[BT-AP01752] Yeast Expression and colon cancers

SKU: 1289540589

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CD59 Polyclonal Antibody, 100ul[BT-AP01752] Yeast Expression and colon cancersApoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12 DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced

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Description

and colon cancers

and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum

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The encoded protein| which functions as a repressor| may play a role in brain development

CD59 Polyclonal Antibody, 100ul[BT-AP01752] Yeast Expression and colon cancersApoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12 DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced

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