LRP2 Polyclonal Antibody, 20ul Metabolic enzymes Three alternatively spliced variants encoding

Three alternatively spliced variants encoding different isoforms have been described for this gene

The protein encoded by this gene is an immunoglobulin-like membrane protein containing several V-type Ig-like domains

Among its related pathways are Metabolism and Pyrimidine metabolism (KEGG)

Mutations of this gene have been reported to be associated with hereditary pheochromocytoma

LRP2 Polyclonal Antibody, 20ul Metabolic enzymes Three alternatively spliced variants encodingThe protein encoded by this gene, low density lipoprotein related protein 2 (LRP2) or megalin, is a multi ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino terminal extracellular domain, a single transmembrane domain, and a short carboxy terminal cytoplasmic tail. The extracellular ligand binding domains bind diverse