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Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in SMC1A result in

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Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in SMC1A result inHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

Mutations in SMC1A result in Cornelia de Lange syndrome

Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy)

Localizes to centrosomes

This protein has been shown to bind CRK-associated substrate

Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Mutations in SMC1A result inHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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