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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette It is an integral membrane

SKU: 12400053940

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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette It is an integral membraneProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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Description

It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel

A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency

Double PHD fingers 2encoded by DPF2 is a member of the d4 domain family

type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI)

PGE synthase Polyclonal Antibody, 100ul Electronic Pipette It is an integral membraneProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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