Btk Monoclonal Antibody, 100ul Immune Cell Analysis This gene is located approximately

This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17

This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor

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and is involved in essential cellular functions

Btk Monoclonal Antibody, 100ul Immune Cell Analysis This gene is located approximatelyThe protein encoded by this gene plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.